Evaluation of an AIF correction algorithm for dynamic susceptibility contrast-enhanced perfusion MRI

Dynamic susceptibility contrast perfusion MRI (with pitfalls)

Since the first studies in the late 1980s and early 1990s, dynamic susceptibility contrast MRI (DSC-MRI, also known as ‘bolus tracking’) has become a very powerful technique for the assessment of perfusion, and perfusion-related parameters (see (1,2) for recent reviews). Despite the need of an exogenous MR agent (cf. arterial spin labeling techniques), DSC-MRI is currently the most common MR pe...

Comparison of methods for quantitative analysis of dynamic susceptibility contrast enhanced brain perfusion MRI

Quantitative cerebral blood flow (CBF) can be obtained from dynamic susceptibility contrast (DSC) MRI using for instance the truncated singular value decomposition (tSVD). Block-circulant SVD and reformulated SVD (rSVD) are modified SVD approaches. The purpose of this study is to compare the different approaches. The optimal truncation thresholds (PSVD) for tSVD and block-circulant SVD are dete...

Diffusion tensor and dynamic susceptibility contrast- enhanced perfusion MRI for the assessment of glioma proliferation

Dynamic susceptibility contrast-enhanced perfusion MR Imaging of Brain Tumors

Dynamic susceptibility contrast MRI

Introduction Quantitative dynamic susceptibility contrast perfusion MRI (DSC-MRI) is based on the monitoring of the first passage of a bolus of contrast agent through the brain tissue and a brain-feeding artery. The contrast agent is injected rapidly by means of an MRinjector in the antecubital vein in the patients arm and a saline flush is used to push the contrast agent into the direction of ...